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Case Reports
. 1999 Apr 26;159(8):877-8.
doi: 10.1001/archinte.159.8.877.

Diabetic gustatory sweating successfully treated with topical glycopyrrolate: report of a case and review of the literature

J D Urman  1 , A M Bobrove
Affiliations
Case Reports

Diabetic gustatory sweating successfully treated with topical glycopyrrolate: report of a case and review of the literature

J D Urman et al. Arch Intern Med. .

Abstract

Background: Gustatory sweating is a more common manifestation of diabetes mellitus than is appreciated. It is a distressing problem that has been difficult to treat safely.

Methods: Daily topical application of glycopyrrolate roll-on lotion was offered as an alternative to oral anticholinergic agents to an 87-year-old woman with long-standing type 2 diabetes mellitus who complained of profuse sweating after eating.

Results: Gustatory sweating was relieved by application of glycopyrrolate and reappeared when the glycopyrrolate was briefly withdrawn to confirm its therapeutic effect.

Conclusion: For moderate to severe symptoms of diabetic gustatory sweating, topical application of glycopyrrolate is safe, effective, well tolerated, and convenient.

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