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. 1978 Nov;93(2):499-514.

Tumor-induced immunosuppression

H Friedman, S Specter, M Watanabe, S H Pan

Tumor-induced immunosuppression

H Friedman et al. Am J Pathol. 1978 Nov.

Abstract

Three tumor systems, including a mastocytoma, plasmacytomas, and a leukemia-lymphoma were studied for their ability to modify humoral immunity to sheep erythrocytes both in vivo and in vitro. All tumors resulted in a depression of the hemolytic antibody plaque-forming cell response in susceptible mice. These studies indicated that the mechanism(s) of suppression, although not fully defined, were different for each model system investigated.

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References

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