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Clinical Trial
. 1999 May;43(5):1289-90.
doi: 10.1128/AAC.43.5.1289.

Correlation between in vitro susceptibility determined by E test and response to therapy with amphotericin B: results from a multicenter prospective study of candidemia

C J Clancy  1 , M H Nguyen
Affiliations
Clinical Trial

Correlation between in vitro susceptibility determined by E test and response to therapy with amphotericin B: results from a multicenter prospective study of candidemia

C J Clancy et al. Antimicrob Agents Chemother. 1999 May.

Abstract

Ninety-nine Candida bloodstream isolates underwent testing for susceptibility to amphotericin B by the E test, and the results were correlated with patients' responses to amphotericin B. The MICs for isolates that were associated with therapeutic failure were significantly higher than the MICs for those associated with therapeutic success. A MIC of >/=0.38 microgram/ml identified isolates likely to be associated with therapeutic failure.

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References

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