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Clinical Trial
. 1999 May;89(5):762-4.
doi: 10.2105/ajph.89.5.762.

The Resource Mothers Program for Maternal Phenylketonuria

P S St James  1 , E Shapiro, S E Waisbren
Affiliations
Clinical Trial

The Resource Mothers Program for Maternal Phenylketonuria

P S St James et al. Am J Public Health. 1999 May.

Abstract

Objectives: The purpose of this study was to measure the effectiveness of resource mothers in reducing adverse consequences of maternal phenylketonuria.

Methods: Nineteen pregnancies in the resource mothers group were compared with 64 pregnancies in phenylketonuric women without resource mothers. Weeks to metabolic control and offspring outcome were measured.

Results: Mean number of weeks to metabolic control was 8.5 (SE = 2.2) in the resource mothers group, as compared with 16.1 (SE = 1.7) in the comparison group. Infants of women in the resource mothers group had larger birth head circumferences and higher developmental quotients.

Conclusions: The resource mothers program described here improves metabolic control in pregnant women with phenylketonuria.

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