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. 1999 Apr;81(4):582-4.

High prevalence of factor V Leiden in healthy Jordanian Arabs

A Awidi  1 , M Shannak, A Bseiso, M A Kailani, M A Kailani, N Omar, B Anshasi, N Sakarneh
Affiliations
  • PMID: 10235443

High prevalence of factor V Leiden in healthy Jordanian Arabs

A Awidi et al. Thromb Haemost. 1999 Apr.

Abstract

The prevalence of APC resistance in healthy Jordanian Arabs was studied. Between October 1996 through September 1997 a total of 400 healthy subjects were studied. There were 212 males and 188 females. APC resistance was studied by functional and DNA methods. There were a total of 52 subjects (13%) who were APC resistant by the functional test. There were 49 subjects (12.25%) who had FV Q506 by DNA test. Of these there were 42 heterozygous and 7 homozygous (allele frequency 0.07). None of the subjects had clinical thrombosis. It is concluded that the prevalence of APC resistance due to FV Q506 is high in Jordanian Arabs.

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