Therapeutic potential of the anti-angiogenesis drug TNP-470
- PMID: 10319017
- PMCID: PMC3220376
- DOI: 10.1046/j.1365-2613.1998.00087.x
Therapeutic potential of the anti-angiogenesis drug TNP-470
Abstract
Neovessel formation is a pre-requisite for tumour growth and dissemination. Inhibition of angiogenesis is a promising approach for the treatment of neoplasms. In recent years, antiangiogenic drugs, such as TNP-470, have entered clinical trials. In this paper, we review the key experimental and clinical data on the role of TNP-470 in anti-tumour treatment.
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