Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1999 Apr;20(4):546-8.

Tissue response of a small saccular aneurysm after incomplete occlusion with a Guglielmi detachable coil

S Shimizu  1 , A Kurata, M Takano, H Takagi, H Yamazaki, Y Miyasaka, K Fujii
Affiliations
Case Reports

Tissue response of a small saccular aneurysm after incomplete occlusion with a Guglielmi detachable coil

S Shimizu et al. AJNR Am J Neuroradiol. 1999 Apr.

Abstract

A 49-year-old woman had a small saccular aneurysm that was incompletely occluded with a Guglielmi detachable coil (GDC). She died from rupture of another aneurysm 42 days after the treatment. Autopsy for the embolized aneurysm revealed no neoendothelium at the aneurysmal neck, but an organized thrombus was observed limited to the periphery of the aneurysmal lumen. Although isolation of the aneurysm was not apparent, loose embolization with this method may help to reinforce the aneurysmal wall.

PubMed Disclaimer

Figures

<sc>fig</sc> 1.
fig 1.
A 49-year-old woman with a small saccular aneurysm. A, Anteroposterior carotid angiogram shows the PTA (arrow) and a small saccular aneurysm at the basilar-superior cerebellar bifurcation (arrowhead). B, Angiogram, after embolization with a GDC, shows partial opacification of the fundus of the aneurysm.
<sc>fig</sc> 2.
fig 2.
Microscopic examination of the small saccular aneurysm after GDC occlusion. A, Low-power photomicrograph shows a cross-section of the aneurysm at the fundus, with a fibrotic component (small star) adjacent to the aneurysmal wall (arrows) and an unformed thrombus at the center of the aneurysm (large star). The location of the coil is indicated (asterisk). (Azan stain; magnification ×100) B, Higher power magnification of the region adjacent to the wall shows fibrous connective tissue with rich capillaries. (Azan stain; magnification ×200)
See this image and copyright information in PMC

Comment in

References

    1. Graves VB, Strother CM, Duff TA, Perl J. Early treatment of ruptured aneurysms with Guglielmi detachable coils: effect on subsequent bleeding. Neurosurgery 1995;37:640-648 - PubMed
    1. Guglielmi G, Viñuela F, Dion J, Duckwiler G. Electrothrombosis of saccular aneurysms via endovascular approach. Part 2: Preliminary clinical experience. J Neurosurg 1991;75:8-14 - PubMed
    1. Malisch TW, Guglielmi G, Viñuela F, et al. Intracranial aneurysms treated with the Guglielmi detachable coil: midterm clinical results in a consecutive series of 100 patients. J Neurosurg 1997;87:176-183 - PubMed
    1. Horowitz MB, Purdy PD, Burns D, Bellotto D. Scanning electron microscopic findings in a basilar tip aneurysm embolized with Guglielmi detachable coils. . AJNR Am J Neuroradiol 1997;18:688-690 - PMC - PubMed
    1. Molyneux AJ, Ellison DW, Morris J, Byrne JV. Histological findings in giant aneurysms treated with Guglielmi detachable coils. J Neurosurg 1995;83:129-132 - PubMed

Publication types