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Review
. 1999 May;24(5):168-73.
doi: 10.1016/s0968-0004(99)01382-1.

DNA chips: promising toys have become powerful tools

D Gerhold  1 , T Rushmore, C T Caskey
Affiliations
Review

DNA chips: promising toys have become powerful tools

D Gerhold et al. Trends Biochem Sci. 1999 May.

Abstract

DNA chips are glass surfaces that represent thousands of DNA fragments arrayed at discrete sites. Hybridization of RNA or DNA-derived samples to DNA chips allows us to monitor expression of mRNAs or the occurrence of polymorphisms in genomic DNA. The technology holds great promise for identifying gene polymorphisms that predispose man to disease, gene regulation events involved in disease progression, and more-effective disease treatments.

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