Review
doi: 10.1016/s0968-0004(99)01384-5.
The WD repeat: a common architecture for diverse functions
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- PMID: 10322433
- DOI: 10.1016/s0968-0004(99)01384-5
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Review
The WD repeat: a common architecture for diverse functions
Trends Biochem Sci.
1999 May.
Free article
Abstract
Our knowledge of the large family of proteins that contain the WD repeat continues to accumulate. The WD-repeat proteins are found in all eukaryotes and are implicated in a wide variety of crucial functions. The solution of the three-dimensional structure of one WD-repeat protein and the assumption that the structure will be common to all members of this family has allowed subfamilies of WD-repeat proteins to be defined on the basis of probable surface similarity. Proteins that have very similar surfaces are likely to have common binding partners and similar functions.
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