Comparison of albumin versus bicarbonate treatment for neonatal metabolic acidosis
- PMID: 10333127
- DOI: 10.1007/s004310051104
Comparison of albumin versus bicarbonate treatment for neonatal metabolic acidosis
Abstract
In this study the effectiveness of 4.5% human albumin was compared with 4.2% sodium bicarbonate for neonatal metabolic acidosis, using a randomised controlled trial. The change in median pH following bicarbonate was more than twice that in the albumin group. This was statistically significant.
Conclusion: In normotensive infants, use of bicarbonate to correct metabolic acidosis may be more effective than use of albumin.
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