Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Jul;5(1):15-7.
doi: 10.1016/0091-3057(76)90281-1.

Papaverine, drug-induced stereotypy and catalepsy and biogenic amines in the brain of the rat

Papaverine, drug-induced stereotypy and catalepsy and biogenic amines in the brain of the rat

W Kostowski et al. Pharmacol Biochem Behav. 1976 Jul.

Abstract

The effects of papaverine on haloperidol-induced catalepsy and apomorphine-induced stereotypy as well as brain monoamines concentrations in rats were studied. Papaverine increased cataleptogenic effect of haloperidol whilst reduced stereotypy induced by apomorphine. Slight but significant decrease in brain dopamine concentration was observed in rats treated with papaverine. The present study indicates that papaverine has influences upon dopaminergic mechanisms in the brain.

PubMed Disclaimer

Similar articles

Cited by

LinkOut - more resources