Review
doi: 10.1007/s000180050297.
Structural view of cadherin-mediated cell-cell adhesion
Affiliations
- PMID: 10336300
- PMCID: PMC11146839
- DOI: 10.1007/s000180050297
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Review
Structural view of cadherin-mediated cell-cell adhesion
Cell Mol Life Sci.
1999 Mar.
Abstract
Following the multiplication of biochemical, biophysical and structural studies describing cadherin molecules and their interactions, several ideas have emerged to explain the mechanisms of cadherin-mediated cell adhesion. Although different models were proposed for cadherin interactions, a consensus has come forth considering lateral dimerization of cadherins as being a central component of the cell-cell adhesion process. This review summarizes the recent development in structural studies of cadherin.
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