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. 1999 Jun;67(6):3166-7.
doi: 10.1128/IAI.67.6.3166-3167.1999.

Immunity in experimental murine filariasis: roles of T and B cells revisited

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Immunity in experimental murine filariasis: roles of T and B cells revisited

S Babu et al. Infect Immun. 1999 Jun.

Abstract

We have reevaluated the contributions of T and B cells in Brugia malayi infection by utilizing knockout mice on a uniform background (C57BL/6J). We find that B-cell-deficient mice are more permissive to infection than T-cell-deficient mice.

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References

    1. Anonymous. Lymphatic filariasis: the disease and its control. Fifth report of the WHO Expert Committee on Filariasis. WHO Tech Rep Ser. 1992;821:1–71. - PubMed
    1. Babu S, Porte P, Klei T R, Shultz L D, Rajan T V. Host NK cells are required for the growth of the human filarial parasite Brugia malayi in mice. J Immunol. 1998;161:1428–1432. - PubMed
    1. Carlow C K, Philipp M. Protective immunity to Brugia malayi larvae in BALB/c mice: potential of this model for the identification of protective antigens. Am J Trop Med Hyg. 1987;37:597–604. - PubMed
    1. Hayashi Y, Nakagaki K, Nogami S, Hammerberg B, Tanaka H. Protective immunity against Brugia malayi infective larvae in mice. I. Parameters of active and passive immunity. Am J Trop Med Hyg. 1989;41:650–656. - PubMed
    1. Nelson F K, Greiner D L, Shultz L D, Rajan T V. The immunodeficient scid mouse as a model for human lymphatic filariasis. J Exp Med. 1991;173:659–663. - PMC - PubMed

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