[Vascular risk factors in non-insulin-dependent diabetes mellitus. Correlation between albuminuria and glycosylated hemoglobin]

Abstract

Objective: This study compared 23 patients with non-insulin-dependent diabetes mellitus (NIDDM) and 28 non-diabetic control subjects, seeking for associations between NIDDM and other cardiovascular risk factors. The relationship of the glycemic control with the risk factor profile was also assessed.

Results: The most outstanding results were: The diabetic group showed higher values in the proportion of subjects with diabetes family history (P < 0.01) and the levels of systolic blood pressure (P < 0.05), total cholesterol (P < 0.05), triglyceridemia (P < 0.001), and total cholesterol to HDL cholesterol ratio (P < 0.01). Within the diabetic group, a positive correlation (r = 0.68, P < 0.001) was found between the percent of glycosylated haemoglobin (HbA1c) and the 24-hour urinary albumin excretion rate (UAER).

Conclusion: We conclude that NIDDM associates to other cardiovascular risk factors. The correlation of HbA1c with UAER suggests a possible relationship between poor diabetic control and some of the secondary diabetic complications.