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. 1999 Jan;113(1):10-2.
doi: 10.1017/s002221510014304x.

Topical aminoglycosides in the management of active mucosal chronic suppurative otitis media

J L Lancaster  1 , Z G Makura, G Porter, M McCormick
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Topical aminoglycosides in the management of active mucosal chronic suppurative otitis media

J L Lancaster et al. J Laryngol Otol. 1999 Jan.

Abstract

Debate has currently re-emerged following a renewed warning issued from the Committee on the Safety of Medicines (CSM) regarding the relative risk of ototoxicity from the use of aminoglycoside-containing drops in patients with tympanic membrane perforations. We present the findings of a survey of ENT consultants, questioning their views and current practice, and we add to the debate by means of a review and discussion of the literature.

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