doi: 10.1007/BF00357209.
Stabilization of double-stranded DNA molecule by non-histone peptidic effector from calf thymus
- PMID: 1034203
- DOI: 10.1007/BF00357209
Item in Clipboard
Stabilization of double-stranded DNA molecule by non-histone peptidic effector from calf thymus
Mol Biol Rep.
1976 Sep.
Abstract
A peptidic effector from calf thymus causes a strong stabilization of DNA double-stranded molecule in vitro. The active factor was isolated from aqueous ultrafiltered thymus extracts and purified by means of chromatography on DEAE-cellulose and then on Dowex 50 WX2. The purified thymic factor was characterized as a peptide of low molecular weight (less than 5000). The biological activity of the thymic factor cannot be attributed to a histone fragment. Melting data of the control DNA and of the DNA-active factor complex in various conditions of ionic strength and dielectric constant of the solution medium are recorded.
Similar articles
-
Low molecular weight peptides controlling transcription are present in the calf thymus chromatin structure.Mol Biol Rep. 1977 Dec;3(6):429-36. doi: 10.1007/BF00808384. Mol Biol Rep. 1977. PMID: 593273
-
Evidence for the presence in calf thymus of a peptidic factor controlling DNA transcription in vitro.Biochim Biophys Acta. 1975 Nov 18;414(1):9-19. doi: 10.1016/0005-2787(75)90121-5. Biochim Biophys Acta. 1975. PMID: 1191703
-
[Physicochemical properties of the thymic lymphocytotropic factor].Ukr Biokhim Zh. 1974 May-Jun;46(3):358-63. Ukr Biokhim Zh. 1974. PMID: 4545879 Ukrainian. No abstract available.
-
Animal DNA-dependent RNA polymerases. 10. General enzymatic properties of purified calf thymus RNA polymerases AI and B.Biochimie. 1974;56(3):319-33. doi: 10.1016/s0300-9084(74)80139-2. Biochimie. 1974. PMID: 4368415 No abstract available.
-
Thymomodulin: biological properties and clinical applications.Med Oncol Tumor Pharmacother. 1989;6(1):5-9. doi: 10.1007/BF02985217. Med Oncol Tumor Pharmacother. 1989. PMID: 2657249 Review.
Cited by
-
Specific thymic peptides-DNA interaction. Correlation with the possible stereochemical kinking scheme of DNA.Mol Biol Rep. 1979 Feb 15;4(4):195-201. doi: 10.1007/BF00777553. Mol Biol Rep. 1979. PMID: 35742
-
Low molecular weight peptides controlling transcription are present in the calf thymus chromatin structure.Mol Biol Rep. 1977 Dec;3(6):429-36. doi: 10.1007/BF00808384. Mol Biol Rep. 1977. PMID: 593273
-
A class of DNA-binding peptides from wheat bud causes growth inhibition, G2 cell cycle arrest and apoptosis induction in HeLa cells.Mol Cancer. 2009 Jul 31;8:55. doi: 10.1186/1476-4598-8-55. Mol Cancer. 2009. PMID: 19646247 Free PMC article.
-
Thymic control of the polyploidization of hepatocytes during aging.Experientia. 1982 Jun 15;38(6):680-1. doi: 10.1007/BF01964092. Experientia. 1982. PMID: 7106236 No abstract available.
-
Effects of a chromatin low molecular weight peptidic fraction on differentiation markers and virus production in Friend leukemia cells.Mol Biol Rep. 1979 Dec 31;5(4):241-9. Mol Biol Rep. 1979. PMID: 93693