doi: 10.1007/BF00508398.
Porcine pituitary peptides with opiate-like activity: partial purification and effects in the rat after intraventricular injection
- PMID: 1034219
- DOI: 10.1007/BF00508398
Item in Clipboard
Porcine pituitary peptides with opiate-like activity: partial purification and effects in the rat after intraventricular injection
Naunyn Schmiedebergs Arch Pharmacol.
1976 Sep.
Abstract
A peptide material with opiate-like activity in the guinea-pig ileum was extracted from porcine pituitaries using a hot glacial acetic acid extraction method and was partially purified by gel filtration. When injected intraventricularly in rats, these purified peptides induced strong analgesia, catelepsy, respiratory depression and other opiate-like effects, which lasted for several hours.
Similar articles
-
Tolerance and dependence induced by morphine-like pituitary peptides in rats.Naunyn Schmiedebergs Arch Pharmacol. 1976 Sep;294(3):297-300. doi: 10.1007/BF00508399. Naunyn Schmiedebergs Arch Pharmacol. 1976. PMID: 1034220
-
A peptide-like substance from pituitary that acts like morphine. 2. Purification and properties.Life Sci. 1975 Jun 15;16(12):1777-82. doi: 10.1016/0024-3205(75)90272-6. Life Sci. 1975. PMID: 1152601 No abstract available.
-
Pharmacological data on dermorphins, a new class of potent opioid peptides from amphibian skin.Br J Pharmacol. 1981 Jul;73(3):625-31. doi: 10.1111/j.1476-5381.1981.tb16797.x. Br J Pharmacol. 1981. PMID: 7195758 Free PMC article.
-
Corticotrophin-like peptide concentrations in the intermediate lobe of rat and guinea-pig pituitaries.J Endocrinol. 1972 Jun;53(3):38-9. J Endocrinol. 1972. PMID: 4339041 No abstract available.
-
Two kinds of opiate receptor.Pol J Pharmacol Pharm. 1977 May-Jun;29(3):165-75. Pol J Pharmacol Pharm. 1977. PMID: 196268
Cited by
-
Endogenous ligands of opiate receptors.Naunyn Schmiedebergs Arch Pharmacol. 1977;297 Suppl 1:S51-2. doi: 10.1007/BF00587776. Naunyn Schmiedebergs Arch Pharmacol. 1977. PMID: 193055
-
Tolerance and dependence induced by morphine-like pituitary peptides in rats.Naunyn Schmiedebergs Arch Pharmacol. 1976 Sep;294(3):297-300. doi: 10.1007/BF00508399. Naunyn Schmiedebergs Arch Pharmacol. 1976. PMID: 1034220
-
Central cardiovascular effects of narcotic analgesics and enkephalins in rats.Br J Pharmacol. 1980;71(2):365-9. doi: 10.1111/j.1476-5381.1980.tb10949.x. Br J Pharmacol. 1980. PMID: 6110456 Free PMC article.