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. 1999 Jun;181(11):3610-2.
doi: 10.1128/JB.181.11.3610-3612.1999.

Salmonella typhimurium IroN and FepA proteins mediate uptake of enterobactin but differ in their specificity for other siderophores

W Rabsch  1 , W Voigt, R Reissbrodt, R M Tsolis, A J Bäumler
Affiliations

Salmonella typhimurium IroN and FepA proteins mediate uptake of enterobactin but differ in their specificity for other siderophores

W Rabsch et al. J Bacteriol. 1999 Jun.

Abstract

Salmonella typhimurium possesses two outer membrane receptor proteins, IroN and FepA, which have been implicated in the uptake of enterobactin. To determine whether both receptors have identical substrate specificities, fepA and iroN mutants and a double mutant were characterized. While both receptors transported enterobactin, the uptake of corynebactin and myxochelin C was selectively mediated by IroN and FepA, respectively.

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Figures

FIG. 1
FIG. 1
Substrate specificity of the S. typhimurium IroN and FepA outer membrane (OM) receptor proteins. PP, periplasmic space. The structures of enterobactin, corynebactin, and myxochelin C are shown above.
See this image and copyright information in PMC

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