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. 1999 Jun;25(6):801-5.
doi: 10.1081/ddc-100102241.

Stability of pilocarpine ophthalmic solutions

C Pilatti  1 , M C Torre, C Chiale, M Spinetto
Affiliations

Stability of pilocarpine ophthalmic solutions

C Pilatti et al. Drug Dev Ind Pharm. 1999 Jun.

Abstract

The stability of pilocarpine and pilocarpine-timolol eyedrop preparations available on the Argentine market was studied. A high-performance liquid chromatographic method that allows the estimation of pilocarpine in the presence of degradation products was used for the study according to the preestablished design. It was found that pilocarpine solutions are stable, while pilocarpine in association with timolol shows significant degradation.

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