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Clinical Trial
. 1999 Mar;7(2):214-8.
doi: 10.1016/s0967-2109(98)00126-4.

A prospective randomized multicentre comparison of expanded polytetrafluoroethylene and gelatin-sealed knitted Dacron grafts for femoropopliteal bypass

B I Robinson  1 , J P Fletcher, P Tomlinson, R D Allen, S J Hazelton, A J Richardson, K Stuchbery
Affiliations
Clinical Trial

A prospective randomized multicentre comparison of expanded polytetrafluoroethylene and gelatin-sealed knitted Dacron grafts for femoropopliteal bypass

B I Robinson et al. Cardiovasc Surg. 1999 Mar.

Abstract

Purpose: To compare graft patency between expanded polytetrafluoroethylene (PTFE) and gelatin-sealed knitted Dacron for femoropopliteal bypass.

Methods: A prospective, multicentre trial was performed in 108 patients randomized to receive either a PTFE or Dacron prosthetic graft. Distal anastomosis was above knee in 75 and below knee in 33 patients.

Results: Primary patency at 1, 2 and 3 years was 72, 52 and 52% for PTFE, and 70, 56 and 47% for Dacron (P = 0.87). Secondary patency at 1, 2 and 3 years was 74, 54 and 54% for PTFE and 78, 70 and 53% for Dacron (P = 0.39). The most significant predictors of early graft failure were poor vessel run-off (P = 0.04) and critical limb ischaemia (P = 0.04).

Conclusion: There was no difference in graft patency between PTFE and Dacron for femoropopliteal bypass.

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