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Review
. 1999 Jun;20(6):254-7.
doi: 10.1016/s0167-5699(99)01469-3.

The chemokine system: redundancy for robust outputs

A Mantovani  1
Affiliations
Review

The chemokine system: redundancy for robust outputs

A Mantovani. Immunol Today. 1999 Jun.

Abstract

Chemokines are redundant in their action on target cells and promiscuous in receptor usage. Moreover, certain cells concomitantly produce several chemokines with an overlapping spectrum of action. Here, Alberto Mantovani argues that such robustness provides a conceptual framework to understand these intriguing aspects of the chemokine system.

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Comment in

  • Cytokine profile data.
    Cohen S. Cohen S. Immunol Today. 2000 Apr;21(4):199-200. doi: 10.1016/s0167-5699(00)01588-7. Immunol Today. 2000. PMID: 10740244 No abstract available.

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