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. 1999 Apr:(4):20-4.

[Immunoenzyme assay for detection of natural antibodies against vasopressin in systemic lupus erythematosus]

[Article in Russian]
M A Miagkova, S O Bachurin, A A Savitskiĭ, M L Stanislav, R M Balabanova, N I Zhokhova, O N Panchenko, Iu A Savitskaia
  • PMID: 10356900

[Immunoenzyme assay for detection of natural antibodies against vasopressin in systemic lupus erythematosus]

[Article in Russian]
M A Miagkova et al. Klin Lab Diagn. 1999 Apr.

Abstract

A solid-phase enzyme immunoassay procedure for detecting natural antibodies to vasopressin (VP) is developed. For this purpose, a VP antigen is synthesized on polymer matrix. Optimal conditions of enzyme immunoassay for detecting antibodies to this antigen in the sera of donors and patients with systemic lupus erythematosus (SLE) are selected. The level of anti-VP antibodies is constant in donors and shifted in SLE patients. Changes in the level of natural antibodies to VP correlate with immunochemical parameters.

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