Angiogenin, a potent mediator of angiogenesis. Biological, biochemical and structural properties

Abstract

Angiogenin is a heparin-binding 14 kDa plasma protein with angiogenic and ribonucleolytic activity. Although its structural features have been extensively studied, an understanding of its physiological role and of how its properties are expressed continues to elude researchers. This article discussed some of the biological, biochemical, and structural properties of angiogenin.