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Case Reports
. 1999 Jun;127(6):718-20.
doi: 10.1016/s0002-9394(98)00426-7.

Acanthamoeba keratitis with live isolates treated with cryosurgery and fluconazole

S P Amoils  1 , C Heney
Affiliations
Case Reports

Acanthamoeba keratitis with live isolates treated with cryosurgery and fluconazole

S P Amoils et al. Am J Ophthalmol. 1999 Jun.

Abstract

Purpose: To report live, active trophozoites in an eye with Acanthamoeba keratitis that resembled Acanthamoeba polyphagia in the anterior chamber fluid obtained by transcorneal tap.

Method: After prediagnostic therapy had failed, we performed cryosurgery to break the corneal cell walls and treated the patient with oral fluconazole.

Results: The condition resolved after 8 weeks of oral fluconazole therapy. Residual leukoma was treated by corneal graft.

Conclusion: Live, motile Acanthamoeba can be isolated from an anterior chamber tap; combination therapy with oral fluconazole after corneal cryosurgery may be effective.

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