[Bronchofiberscope and catheter intervention in treatment of multi-drug resistant pulmonary tuberculosis]
- PMID: 10374446
[Bronchofiberscope and catheter intervention in treatment of multi-drug resistant pulmonary tuberculosis]
Abstract
Objective: To evaluate the clinical value of bronchofiberscope and catheter intervention in treatment of multi-drug resistant pulmonary tuberculosis.
Method: Forty-eight patients with multi-drug resistant pulmonary tuberculosis were treated by injecting ofloxacin and amikacin through bronchofiberscope and catheter in addition to chemotherapy, while forty controls were treated by chemotherapy only.
Result: At the end of the treatment, the sputum conversion rate was 92%, radiographic improvement rate 96% and cavity closing rate 27% in the treatment group, all of which were higher than the controls (63%, 58% and 10% respectively) (P < 0.01-0.05). No complication and obvious adverse reaction were observed.
Conclusion: The efficacy of bronchofiberscope and catheter intervention in addition to chemotherapy is better than only chemotherapy in treatment of multi-drug resistant pulmonary tuberculosis.
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