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Clinical Trial
. 1997 Dec;20(6):354-7.

[Bronchofiberscope and catheter intervention in treatment of multi-drug resistant pulmonary tuberculosis]

[Article in Chinese]
Affiliations
  • PMID: 10374446
Clinical Trial

[Bronchofiberscope and catheter intervention in treatment of multi-drug resistant pulmonary tuberculosis]

[Article in Chinese]
Y Zhang et al. Zhonghua Jie He He Hu Xi Za Zhi. 1997 Dec.

Abstract

Objective: To evaluate the clinical value of bronchofiberscope and catheter intervention in treatment of multi-drug resistant pulmonary tuberculosis.

Method: Forty-eight patients with multi-drug resistant pulmonary tuberculosis were treated by injecting ofloxacin and amikacin through bronchofiberscope and catheter in addition to chemotherapy, while forty controls were treated by chemotherapy only.

Result: At the end of the treatment, the sputum conversion rate was 92%, radiographic improvement rate 96% and cavity closing rate 27% in the treatment group, all of which were higher than the controls (63%, 58% and 10% respectively) (P < 0.01-0.05). No complication and obvious adverse reaction were observed.

Conclusion: The efficacy of bronchofiberscope and catheter intervention in addition to chemotherapy is better than only chemotherapy in treatment of multi-drug resistant pulmonary tuberculosis.

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