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Review
. 1999 Jun;6(6):R167-75.
doi: 10.1016/S1074-5521(99)80044-1.

Histidine kinases and two-component signal transduction systems

M C Pirrung  1
Affiliations
Review

Histidine kinases and two-component signal transduction systems

M C Pirrung. Chem Biol. 1999 Jun.

Abstract

The phosphorylation of histidine is the first step in many signal transduction cascades in bacteria, yeast and higher plants. The transfer of a very reactive phosphoryl group from phosphorylated histidine kinase to an acceptor is an essential step in many cellular signaling responses.

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