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Review
. 1999 Jun;11(3):256-64.
doi: 10.1016/s0952-7915(99)80042-9.

Signal transduction from the B cell antigen-receptor

K S Campbell  1
Affiliations
Review

Signal transduction from the B cell antigen-receptor

K S Campbell. Curr Opin Immunol. 1999 Jun.

Abstract

Ligation of the B cell antigen-receptor triggers an intricate maze of intercalated biochemical events that ultimately affect B cell biological responses. Recent advances have helped to connect many loose ends by identifying key adaptor proteins, such as BLNK/SLP-65, defining crucial roles for phosphatidylinositol-3-kinase and mapping pathways controlling the mitogen-activated protein kinases (ERK, JNK and p38).

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