Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1999 Jul 1;341 ( Pt 1)(Pt 1):11-4.

A conserved RGD (Arg-Gly-Asp) motif in the transferrin receptor is required for binding to transferrin

V Dubljevic  1 , A Sali, J W Goding
Affiliations
Comparative Study

A conserved RGD (Arg-Gly-Asp) motif in the transferrin receptor is required for binding to transferrin

V Dubljevic et al. Biochem J. .

Abstract

The transferrin receptor contains a highly conserved Arg-Gly-Asp (RGD) sequence in the C-terminal region where transferrin is thought to bind. RGD sequences are commonly involved in cell adhesion. This sequence is crucial for transferrin binding, suggesting possible evolutionary links between molecules mediating iron uptake and cell adhesion.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1472-7 - PubMed
    1. Gene. 1997 Oct 15;199(1-2):123-31 - PubMed
    1. Proc Natl Acad Sci U S A. 1983 Apr;80(8):2258-62 - PubMed
    1. Proc Natl Acad Sci U S A. 1983 Apr;80(8):2263-6 - PubMed
    1. Cell. 1984 May;37(1):95-103 - PubMed

Publication types

LinkOut - more resources