Turn up the HEAT
- PMID: 10378263
- DOI: 10.1016/s0969-2126(99)80060-4
Turn up the HEAT
Abstract
The recently determined crystal structure of the PR65/A subunit of protein phosphatase 2A reveals the architecture of proteins containing HEAT repeats. The structural properties of this solenoid protein explain many functional characteristics and account for the involvement of solenoids as scaffold, anchoring and adaptor proteins.
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