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Review
. 1999 Jul;20(7):312-6.
doi: 10.1016/s0167-5699(99)01476-0.

CD5 expression in human B-cell populations

P Youinou  1 , C Jamin, P M Lydyard
Affiliations
Review

CD5 expression in human B-cell populations

P Youinou et al. Immunol Today. 1999 Jul.

Abstract

The origin of CD5+ B cells remains controversial. The differential response to ligation of CD5 resulting in apoptosis or proliferation provides insight into its roles in distinct human B cells. Here, Pierre Youinou, Christophe Jamin and Peter Lydyard review current knowledge of B-1 and B-2 cells, and propose that CD5 has different functions when expressed by different B-cell subpopulations.

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