Review
doi: 10.1126/science.284.5423.2118.
Chemical etiology of nucleic acid structure
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- PMID: 10381870
- DOI: 10.1126/science.284.5423.2118
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Review
Chemical etiology of nucleic acid structure
Science.
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Abstract
Systematic chemical studies indicate that the capability of Watson-Crick base-pairing is widespread among potentially natural nucleic acid alternatives taken from RNA's close structural neighborhood. A comparison of RNA and such alternatives with regard to chemical properties that are fundamental to the biological function of RNA provides chemical facts that may contain clues to RNA's origin.
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