Complex vascular lesions at autopsy in a patient with phentermine-fenfluramine use and rapidly progressing pulmonary hypertension
- PMID: 10383810
- DOI: 10.5858/1999-123-0539-CVLAAI
Complex vascular lesions at autopsy in a patient with phentermine-fenfluramine use and rapidly progressing pulmonary hypertension
Abstract
Anorectic agents, such as aminorex and fenfluramine derivatives, have been associated previously with the development of primary pulmonary hypertension. The combination diet drug phentermine-fenfluramine (or "phen-fen") was recently marketed in the United States. We describe a case of a 39-year-old woman with rapidly progressing, fatal pulmonary hypertension following administration of phentermine-fenfluramine. Autopsy was remarkable for complex pulmonary vascular lesions most consistent with thrombotic arteriopathy.
Comment in
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Complex vascular lesions at autopsy in a patient with phentermine-fenfluramin.Arch Pathol Lab Med. 2000 Jun;124(6):801-2. doi: 10.5858/2000-124-801b-IR. Arch Pathol Lab Med. 2000. PMID: 10835505 No abstract available.
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