Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 Oct;19(5):613-24.
doi: 10.1023/a:1006932418220.

Distribution of 1,25-dihydroxyvitamin D3 receptor immunoreactivity in the rat olfactory system

Affiliations

Distribution of 1,25-dihydroxyvitamin D3 receptor immunoreactivity in the rat olfactory system

S D Glaser et al. Cell Mol Neurobiol. 1999 Oct.

Abstract

1. The rat olfactory system contains numerous target sites for 1,25-dihydroxyvitamin D3, as determined by receptor protein (VDR) immunocytochemistry and in situ hybridization. 2. Nuclear and cytoplasmic VDR immunoreactivity as well as the corresponding hybridization signal was observed in neurons in the olfactory epithelium, the olfactory bulb, and throughout the limbic system in locations also known to be glucocorticoid targets. 3. The widespread distribution of VDR indicates the distinct functional importance of 1,25-dihydroxyvitamin D3 for olfactory perception.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Alheid, G. F., de Olmos, J. S., and Beltramino, C. A. (1995). Amygdala and extended amygdala. In Paxinos, G. (ed.), The Rat Nervous System, Academic Press, Sydney, pp. 515–523.
    1. Ayer-Lelievre, C., Olson, L., Ebendal, T., Seiger, A., and Person, H. (1988). Expression of the nerve growth factor gene in hippocampal neurons. Science240:1339–1341. - PubMed
    1. Baker, A. R., McDonnell, D. P., Hughes, M., Crisp, T. M., Mangelsdorf, D. J., Haussler, M. R., Pike, J. W., Shine, J., and O'Malley, B. W. (1988). Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proc. Natl. Acad. Sci. USA85:3294–3298. - PMC - PubMed
    1. Beato, M., Herrlich, P., and Schütz, G. (1995). Steroid hormone receptors: many actors in search of a plot. Cell83:851–857. - PubMed
    1. Breedlove, S. M. (1994). Sexual differentiation of the human nervous system. Annu. Rev. Psychol.45:389–418. - PubMed

Publication types

Substances

LinkOut - more resources