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. 1999 Jul;43(7):1808-10.
doi: 10.1128/AAC.43.7.1808.

In vitro susceptibilities of Chlamydia pneumoniae isolates from German patients and synergistic activity of antibiotic combinations

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In vitro susceptibilities of Chlamydia pneumoniae isolates from German patients and synergistic activity of antibiotic combinations

H M Freidank et al. Antimicrob Agents Chemother. 1999 Jul.

Abstract

The susceptibilities of six Chlamydia pneumoniae type strains and of six German patient isolates to erythromycin, azithromycin, roxithromycin, clarithromycin, doxycycline, ofloxacin, and rifampin were investigated. MICs and minimal chlamydicidal concentrations were all within the ranges reported previously. Combinations of azithromycin with either ofloxacin, doxycycline, or rifampin, as well as combinations of three antibiotics (rifampin, azithromycin, and ofloxacin or doxycycline), showed synergistic activity against C. pneumoniae.

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References

    1. Agacfidan A, Moncada J, Schachter J. In vitro activity of azithromycin (CP-62,993) against Chlamydia trachomatis and Chlamydia pneumoniae. Antimicrob Agents Chemother. 1993;37:1746–1748. - PMC - PubMed
    1. Beale A S, Masson N D. Susceptibility of Chlamydia pneumoniae to oral agents commonly used in the treatment of respiratory infection. J Antimicrob Chemother. 1994;34:1072–1074. - PubMed
    1. Block S, Hedrick J, Hammerschlag M R, Cassell G H, Craft J C. Mycoplasma pneumoniae and Chlamydia pneumoniae in pediatric community-acquired pneumonia: comparative efficacy and safety of clarithromycin vs. erythromycin ethylsuccinate. Pediatr Infect Dis J. 1995;14:471–477. - PubMed
    1. Eliopoulos G M, Moellering R C., Jr . Antimicrobial combinations. In: Lorian V, editor. Antibiotics in laboratory medicine. Baltimore, Md: Williams & Wilkins; 1996. pp. 330–393.
    1. Falck G, Gnarpe J, Gnarpe H. Persistent Chlamydia pneumoniae infection in a Swedish family. Scand J Infect Dis. 1996;28:271–273. - PubMed

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