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Review
. 1999 Jul 6;96(14):7614-6.
doi: 10.1073/pnas.96.14.7614.

Postmitochondrial regulation of apoptosis during heart failure

Affiliations
Review

Postmitochondrial regulation of apoptosis during heart failure

J C Reed et al. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
Postmitochondrial regulation of apoptosis. Mitochondria have been reported to sequester and release several proteins implicated in apoptosis, including Cyt c, pro-caspases-2, -3, and -9, and AIF, a flavoprotein that induces DNA degradation and other manifestations of nuclear apoptosis (60). Several steps within the Cyt c pathway may be subject to suppression by anti-apoptotic proteins (red).

Comment on

References

    1. Cryns V, Yuan Y. Genes Dev. 1998;12:1551–1570. - PubMed
    1. Salvesen G S, Dixit V M. Cell. 1997;91:443–446. - PubMed
    1. Schwartz L M, Smith S W, Jones M E E, Osbourne B A. Proc Natl Acad Sci USA. 1993;90:980–984. - PMC - PubMed
    1. Gottlieb R A, Burleson K O, Kloner R A, Babior B M, Engler R L. J Clin Invest. 1994;94:1621–1628. - PMC - PubMed
    1. Ohno M, Takemura G, Ohno A, Misao J, Hayakawa Y, Minatoguchi S, Fujiwara T, Fujiwara H. Circulation. 1998;98:1355–1357. - PubMed