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Review
. 1999 Jun;11(3):352-7.
doi: 10.1016/S0955-0674(99)80049-0.

mRNA polyadenylation and its coupling to other RNA processing reactions and to transcription

L Minvielle-Sebastia  1 , W Keller
Affiliations
Review

mRNA polyadenylation and its coupling to other RNA processing reactions and to transcription

L Minvielle-Sebastia et al. Curr Opin Cell Biol. 1999 Jun.

Abstract

Eukaryotic mRNA precursors are processed at their 3' ends by a coupled cleavage/polyadenylation reaction. In recent years, most of the factors involved in 3'-end processing have been identified and evidence has been presented for the coupling of mRNA 3'-end formation to capping, splicing and transcription. These links are important for the quality control of the mRNA during synthesis.

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