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Review
. 1999 Jun;11(3):372-7.
doi: 10.1016/S0955-0674(99)80052-0.

Nuclear organization of pre-mRNA splicing factors

J E Sleeman  1 , A I Lamond
Affiliations
Review

Nuclear organization of pre-mRNA splicing factors

J E Sleeman et al. Curr Opin Cell Biol. 1999 Jun.

Abstract

The splicing of mRNA precursors (pre-mRNA) in the nucleus is catalyzed by a complex machinery termed the spliceosome. In order to understand how it functions in vivo, it is essential to complement biochemical analyses with a detailed study of how spliceosome components are organized within the nucleus.

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