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. 1999 Jun 21;9(12):1663-6.
doi: 10.1016/s0960-894x(99)00261-9.

Landomycin A inhibits DNA synthesis and G1/S cell cycle progression

R T Crow  1 , B Rosenbaum, R Smith 3rd, Y Guo, K S Ramos, G A Sulikowski
Affiliations

Landomycin A inhibits DNA synthesis and G1/S cell cycle progression

R T Crow et al. Bioorg Med Chem Lett. .

Abstract

Landomycin A was found to inhibit the uptake of [3H]thymidine into DNA in murine smooth muscle cells indicating decreased DNA synthesis. Subsequent studies showed that landomycin A inhibits cell cycle progression.

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