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. 1999 Jun;34(6):563-70.
doi: 10.1007/s11745-999-0399-z.

Lymphatic absorption of phytosterol oxides in rats

A Grandgirard  1 , J P Sergiel, M Nour, J Demaison-Meloche, C Giniès
Affiliations

Lymphatic absorption of phytosterol oxides in rats

A Grandgirard et al. Lipids. 1999 Jun.

Abstract

Two of the main classes of oxyphytosterols (7-keto and epoxides) were synthesized from sitosterol and campesterol and given to mesenteric duct-cannulated adult male rats. Lymph was collected during 24 h and was analyzed for oxysterols. The results showed that the lymphatic recovery of the phytosterol oxides was low: 4.7% of the given dose for epoxy derivatives and 1.5% for 7-keto compounds. The campesterol oxides presented a better absorption than the sitosterol oxides. During the process of absorption, the epoxyphytostanols were also partly transformed in campestanetriol and stigmastanetriol.

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