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Comparative Study
. 1999 Jul;77(3-4):153-61.
doi: 10.1016/s0304-3991(99)00043-1.

Leginon: a system for fully automated acquisition of 1000 electron micrographs a day

C S Potter  1 , H Chu, B Frey, C Green, N Kisseberth, T J Madden, K L Miller, K Nahrstedt, J Pulokas, A Reilein, D Tcheng, D Weber, B Carragher
Affiliations
Comparative Study

Leginon: a system for fully automated acquisition of 1000 electron micrographs a day

C S Potter et al. Ultramicroscopy. 1999 Jul.

Abstract

We have developed a system to automatically acquire large numbers of acceptable quality images from specimens of negatively stained catalase, a biological protein which forms crystals. In this paper we will describe the details of the system architecture and analyze the performance of the system as compared to a human operator. The ultimate goal of the system if to automate the process of acquiring cryo-electron micrographs.

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