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. 1999 Jul 5;9(13):1757-60.
doi: 10.1016/s0960-894x(99)00285-1.

Synthesis and identification of conformationally constrained selective MMP inhibitors

J N Freskos  1 , J J McDonald, B V Mischke, P B Mullins, H S Shieh, R A Stegeman, A M Stevens
Affiliations

Synthesis and identification of conformationally constrained selective MMP inhibitors

J N Freskos et al. Bioorg Med Chem Lett. .

Abstract

We have discovered a new series of potent conformationally constrained MMP Inhibitors that are selective for MMP-13 over MMP-1.

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