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Review
. 1999 Jul;141(1):127-31.
doi: 10.1046/j.1365-2133.1999.02933.x.

Paraneoplastic cicatricial pemphigoid

J Setterfield  1 , P J Shirlaw, Z Lazarova, B M Bryant, B S Bhogal, K Harman, S J Challacombe, M M Black
Affiliations
Review

Paraneoplastic cicatricial pemphigoid

J Setterfield et al. Br J Dermatol. 1999 Jul.

Abstract

We report a 39-year-old woman with antiepiligrin cicatricial pemphigoid (CP) in association with non-small cell carcinoma of the lung. At presentation, mucosal lesions showed minimal response to combined systemic immunosuppressive agents. Following the diagnosis of non-small cell lung carcinoma and subsequent treatment with gemcitabine (a second-line chemotherapeutic agent), a significant reduction in both tumour mass and mucosal blistering was observed. Metastatic disease was subsequently associated with recurrent oral erosions. We believe this patient represents the first reported case of paraneoplastic CP.

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