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Comparative Study
. 1999 Jul;79(4):301-4.
doi: 10.1080/000155599750010715.

Clinical and dermatoscopic diagnosis of malignant melanoma. Assessed by expert and non-expert groups

H Lorentzen  1 , K Weismann, C S Petersen, F G Larsen, L Secher, V Skødt
Affiliations
Free article
Comparative Study

Clinical and dermatoscopic diagnosis of malignant melanoma. Assessed by expert and non-expert groups

H Lorentzen et al. Acta Derm Venereol. 1999 Jul.
Free article

Abstract

We investigated the nosographic and diagnostic probabilities and likelihood ratios of dermatoscopy in order to evaluate the method's role in decision-making regarding melanoma. Clinical slides and dermatoscopic photos were obtained from 232 patients referred for dermatoscopy. Four dermatoscopy "experts" and 5 "non-experts" assessed the slides. Diagnoses were compared with histopathology. Sensitivity of the clinical assessments was 0.78 vs. 0.69 ("experts" vs. "non-experts"), sensitivity of dermatoscopy assessment was 0.83 vs. 0.69 (p = 0.04). The expert group demonstrated increased specificity (from 0.89 to 0.94) when applying dermatoscopy compared with clinical assessment alone (p=0.03). Positive likelihood ratios were doubled in the "expert group" and the negative likelihood ratios improved 25% with dermatoscopy compared with clinical assessment.

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