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Review
. 1999 Aug;24(8):317-20.
doi: 10.1016/s0968-0004(99)01425-5.

Chemical genetics: exploring and controlling cellular processes with chemical probes

C M Crews  1 , U Splittgerber
Affiliations
Free article
Review

Chemical genetics: exploring and controlling cellular processes with chemical probes

C M Crews et al. Trends Biochem Sci. 1999 Aug.
Free article

Abstract

The new field of chemical biology brings together chemists and biologists who are seeking to understand and mimic the natural world. One research strategy in this new field is the development of biologically active small molecules as molecular probes. This approach, which has been called 'chemical' genetics, has allowed elucidation of several pathways that have been difficult to study using traditional genetic approaches.

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