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Review
. 1999 May;10(3):99-114.
doi: 10.1177/095632029901000301.

Cell-based and animal models for hepatitis B and C viruses

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Free article
Review

Cell-based and animal models for hepatitis B and C viruses

R F Schinazi et al. Antivir Chem Chemother. 1999 May.
Free article

Abstract

Reliable cell-based assays and animal models have been developed for evaluating agents against hepatitis B virus. Although much progress has been made, in vitro and in vivo assays for hepatitis C virus are still on the horizon. Advances towards establishing inexpensive and reliable experimental models have accelerated the development of therapeutic modalities for these life-threatening viral infections. The characterization of well-defined viral targets coupled with improved molecular diagnostic technologies have illuminated this field.

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