[Synapsoarchitectonics of cerebral cortex: ontogenetic aspects]

Abstract

The formation of synapses in ontogenesis is an important problem of neuromorphology. The bulk of synapses of the developing brain is shown to be formed on the basis of prespecialization of membranes. In early ontogenesis, the bulk of the formed synapses represents asymmetric contacts. In postnatal ontogenesis, a synapse forms due to the simultaneous occurrence of specialization of membranes and synaptic vesicles by forming an active "dot" zone. Systemogenesis, such as the general law of brain development plays an important role in understanding the functional importance of the mechanisms of synaptic maturation.