Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999;13(16):1663-70.
doi: 10.1002/(SICI)1097-0231(19990830)13:16<1663::AID-RCM695>3.0.CO;2-T.

Energy-resolved mass spectrometry: a comparison of quadrupole cell and cone-voltage collision-induced dissociation

A G Harrison  1
Affiliations

Energy-resolved mass spectrometry: a comparison of quadrupole cell and cone-voltage collision-induced dissociation

A G Harrison. Rapid Commun Mass Spectrom. 1999.

Abstract

Collision-induced dissociation (CID) can be effected in the interface region between atmospheric pressure ionization sources and single quadrupole mass analyzers. By varying the electric field in these cone-voltage CID experiments energy-resolved mass spectra can be obtained leading to breakdown graphs exploring the energy evolution of the fragmentation pathways. The breakdown graphs obtained from these cone-voltage CID studies are very comparable to those obtained by varying the collision energy in the quadrupole collision cell of a BEqQ mass spectrometer. The comparison has been made for the protonated peptides H-Leu-Gly-Gly-OH, H-Gly-Leu-Gly-OH, H-Gly-Gly-Leu-OH and Leu-enkephalin

PubMed Disclaimer

Publication types

LinkOut - more resources