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Review
. 1999 Aug;10(2):193-5.
doi: 10.1002/(sici)1522-2586(199908)10:2<193::aid-jmri13>3.0.co;2-2.

Unexpected MR-T1 enhancement of endocrine liver metastases with mangafodipir

D Mathieu  1 , C Coffin, H Kobeiter, F Caseiro-Alves, A Mahfouz, A Rahmouni, T Diche
Affiliations
Review

Unexpected MR-T1 enhancement of endocrine liver metastases with mangafodipir

D Mathieu et al. J Magn Reson Imaging. 1999 Aug.

Abstract

With the use of available liver magnetic resonance contrast agents, such as mangafodipir (Mn-DPDP), liver metastases do not exhibit enhancement on T1-weighted images. This absence of enhancement is due to the lack of hepatocytes within these tumors. The purpose of this report is to demonstrate an unexpected enhancement on T1-weighted images 30 minutes after injection of mangafodipir, in the case of endocrine liver metastases from a non-hyperfunctioning neuroendocrine pancreatic tumor. Different hypotheses could explain this unexpected enhancement, such as increased arterial tumoral flow or high metabolic activity. Contrary to liver metastases of other origins, Mn-DPDP enhancement can be present in neuroendocrine metastases. J. Magn. Reson. Imaging 1999;10:193-195.

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