Heavy metal nephropathy of rodents
- PMID: 104422
- DOI: 10.1177/0300985878015s0507
Heavy metal nephropathy of rodents
Abstract
Heavy metal nephropathy is a pathologic entity of the renal tubular epithelium of rats, evoked by lead, gold, and other heavy metals. It is characterized acutely by coagulative necrosis, subacutely by cortical fibrosis, and chronically by cytomegaly and karyomegaly. Finally, adenomas develop, some of which become malignant.
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