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Review
. 1999 Aug;9(4):476-83.
doi: 10.1016/S0959-440X(99)80067-0.

Structure of the respiratory NADH:ubiquinone oxidoreductase (complex I)

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Review

Structure of the respiratory NADH:ubiquinone oxidoreductase (complex I)

N Grigorieff. Curr Opin Struct Biol. 1999 Aug.

Abstract

Three-dimensional structures of NADH:ubiquinone oxidoreductase (or complex I) from the respiratory chain of mitochondria and bacteria have been recently studied by electron microscopy. The low-resolution structures all reveal a characteristic L shape for complex I; however, some of the differences among these structures may have important implications for the location of the functional elements of complex I, for example, the ubiquinone-binding site.

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Comment in

  • Membrane proteins.
    Kühlbrandt W, Gouaux E. Kühlbrandt W, et al. Curr Opin Struct Biol. 1999 Aug;9(4):445-7. doi: 10.1016/S0959-440X(99)80062-1. Curr Opin Struct Biol. 1999. PMID: 10449380 No abstract available.

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